ZHANG Xiao-Jing, et al. The distribution of HPV infections in women seeking for examination in Chongqing yongchuan area[J]. Journal of Chongqing Medical University, 2010,35(9):1407-1410.
ZHANG Xiao-Jing, et al. The distribution of HPV infections in women seeking for examination in Chongqing yongchuan area[J]. Journal of Chongqing Medical University, 2010,35(9):1407-1410. DOI: 10.13406/j.cnki.cyxb.2010.09.039.
Objective:To comprehend the status of infection as well as distribution of types of Human papillomaviruses(HPV) and provide evidence for diagnosis and prevention.Methods:665 samples were detected and genotyped with the technology of gene chips.The data was analyzed with the statistical software SPSS13.0.Results:①37.65% of those samples were detected positive for HPV infection and 20 HPV genotypes were detected successfully.Among them
27.25% were infected by single HPV genotype
7.22% were infected by two genotypes and 3.18% were infected by three genotypes.In the single infection of HPV
the percentages of 16
6
11
33
58
43
18 were 9.92%
5.74%
4.36%
1.32%
1.05%
1.02%
0.75% respectively
and the rate of others of other genotypes were 3.29%.②The rates of different age group of high risk HPV were 14.1%(≤20)
15.2%(21~30)
17.2%(31~40)
17.3%(>40)(χ2=3.0
P>0.05).The rates of different age group of low risk HPV were 20.3%(≤20)
11.7%(21~30)
10.1%(31~40)
10.1%(>40)(χ2=23.28
P<0.01)
a statistically significant difference between the groups.Conclusion:①In the area of Sichuan
HPV infection situation was comparatively severe and most were single infection.Among the high risk HPV infections
HPV16 prevalence was highest
and among the low risk HPV infections
types 6 and 11 were the most prevalent.②Age had certain something to do with HPV infection.③The present study palyed an important role in preventing and treating the diseases caused by HPV
such as cervical cancer
condylomata acuminate.
关键词
人乳头瘤病毒型别分布宫颈癌尖锐湿疣
Keywords
Human papillomavirusesTypes distributioncervical cancerCondylomata acuminate