Objective:To analyse the clinical characteristics

therapy and prognostics of ANCA associated small vessel vasculitis.Methods:Collect the clinical data of 16 cases diagnosed of ANCA associated small vessel vasculitis

analysis the clinical manifestation

auxiliary examination

therapy and prognostics.Results:There were 11 males and 5 famales

aged from 33 to 92 and by an average of 61±17.3 years old.There were non-specific clinical manifestations at the onset.16 cases manifest more or less renal damage and 3 with additional bellows lesion.9 cases subjected to renal biopsy and with the results as follows:all of them were indicated with segmental glomerular necrosis and crescent formation

1 case prompted a small number of immunoglobulin IgG and complement C3 deposition by immunofluorescent.16 3 monthes to 2years)

except 1 relapse at the time of 13 monthes after ANCA negatived.Conclusion:The onset clinical manifestations are multiplex of ANCA associated small vessel vasculitis

kidney is the main affected organ.The renal function may not associated with prognosis directly

and mass hematuria

erythrocyte cast

immune complex deposit may relevant to relapse.