Objective:To investigate the risk factors of pulmonaryfungal infection in intensive care unit(ICU)

and discuss the strategy of prevention and treatment.Methods:Thirty-four patients with pulmonary fungal infection in ICU of our Hospital from Jan.2004 to Jan. 2009 were analyzed retrospectively

including primarily diseases

application of antibiotics

adrenal cortical hormone and virulence opera-tion

therapy and turnover.Results:All patients were accepted the therapies of broad spectrum antibiotics and glucocorticoids for long time before definite diagnosis of pulmonary fungal infection.Theire average time that the patients staying in hospital was 45.6 d.The clinical symptoms and imaging examinations were untypica.l Blastomyces albicans was the main pathogen.After the antifungal agents and supportive treatment used in time

33cases(97%)were cured and 1cases(3%)died.Conclusion:The major risk factors of children pulmonary fungal infection are long-time use of broad spectrum antibiotics and glucocorticoids.The pulmonary fungal infection can decrease by rationaluse of broad spectrum antibiotics and glucocorticoids

decreasing the unnecessary invasive operations

strengthening the supportive therapies ofmicro-ecosystem

and applying the antifungal agents in time.