Objective:To study the curative effect and reliability of fastigial nucleus stimulation (FNS)in treating nonmalignant arrhythmia. Methods:In a random period

FNS was used to treat 45 patients

who consulted doctors for repetitive palpitation

had cardiac arrhythmia (supraventricular premature beats

supraventricular runs

ventricular premature beats)confirmed by 24 h Holter monitoring electrocardiogram

and whose state of illness did not improve after being treated by one or several antiarrhythmic drugs. After those patients were treated by FNS 40 minutes a time

two times a week

for 15 times

the changes of 24 h Holter monitoring electrocardiogram were observed. Results:Before and after treatment by FNS

the numbers of SVPB were (3 358.5±5 044.0)/24 h and (1 142.8±2 722.3)/24 h respectively;those ofVPBwere(10 469.7±9 464.9)/24 h and(4 379.4±8 143.3)/24 h respectively;normalized low frequencies(LFnorm)were(35.28±7.04)nU and(31.82±7.35)nU respectively;normalized high frequencies(HFnorm)were (24.32±4.18)nU and (26.84±4.66)nU respectively. LF/HF was 1.47±0.32 and 1.21±0.29 respectively. The differences between pre-treatment and post-treatment indices were all statistically significant (P<0.05). Effective rates of SVPB and VPB by FNS were 64.44% and 63.89% respectively. Supraventricular runs paroxysm markedly decreased after treatment (P<0.05). FNS did not cause adverse reaction. Conclusion:FNS can significantly decrease SVPB and VPB. FNS can improve cardiac autonomic nervous dysfunction in the patients with cardiac arrhythmia. FNS is a therapeutic tool which is safe

effective

easy to be operated and affordable

and it is worth researching and spreading further.