Objective:Use transcranial Doppler ultrasound(TCD)to investigate cerebrovascular hemodynamic changes in patients with essential hypertension and provide clinical evidence for prevention of stroke.Methods:2 025 individuals who joined in physical examination were randomly selected and classified into two groups as hypertension group of 892 cases and control group of 1 133 cases.Hypertesion group is divided into 3 subgroups as normal hypertension group

complicated with glucose or lipid metabolism disorder groups.The main observational parameters through their TCD tests were systolic blood flow velocity(Vs)

diastolic blood flow velocity(Vd)

mean velocity(Vm)

resistant index(RI)

pulsatility index(PI).Results:(1)The basilar artery blood flow velocity(Vs

Vm

Vd)of patients with essential Hypertension were significantly lower than control group

Vd of middle cerebral artery decreased in hypertensive patients.On the other hand

RI and PI of the patients were higher than control group(P<0.01).(2)In hypertesion complicated with glucose metabolism disorder group

Vm and Vd decreased

RI and PI increased and has significant difference with the other groups.However

hypertesion complicated with hyperlipemia group didn’t show significance with pure hypertension group.(3)The abnormal possibility of TCD in young hypertensive patients is 34.5%.The major cause is cerebral vasospasm(69.2%).The abnormal possibility in older hypertensive patients is 79.0%

the major cause is angiosclerosis(51.3%).Conclusion:Early essential hypertension can cause functional changes in cerebral vessels

basilar artery is especially sensitive.TCD can reflect cerebrovascular hemodynamic changes and cerebral flow velocity is influenced by multiple interacting factors such as age

diabetes and hyperlipemia.