Objective:To identify clinical and MRI images characteristics in patients with multiple sclerosis(MS).Methods:180 patients who fulfilled the MS diagnostic criteria of McDonald were selected to undergo MRI scans of the brain and spinal cord.The clinical characteristics and the MRI images of the brain and spinal cord were analyzed.The patient’ s neurological disability was assessed using the Kurtzke expanded disability states scale(EDSS)scores.Results:(1)The one of the main motivations is the upper respiratory tract infection(27.78%)

and the most frequent onset symptom was weakness in one or more limbs(54.4%).(2)The patients with simple brain lesions were involved in 45.56%

followed by the spinal cords(29.44%)

and both brain and spinal cord involvement in 25%.The EDSS scores were statistical differences among the patients with the simple brain involvement

simple spinal cord involvement

both brain and spinal cord involvements(P<0.05).(3)The lower cervical and upper thoracic spinal cords were easily involved

the length of cord lesions which were less than three vertebral segments was 74.49%

the 1～2 segments were the most frequent involved.Conclusion:The combination of clinical characteristics and conventional MRI can improve the diagnosis and monitor the progressive for patients with MS.