LI Ge, et al. Experimental study on the expression of survivin in renal clear cell carcinoma 786-O[J]. Journal of Chongqing Medical University, 2010,35(1):40-42.
LI Ge, et al. Experimental study on the expression of survivin in renal clear cell carcinoma 786-O[J]. Journal of Chongqing Medical University, 2010,35(1):40-42. DOI: 10.13406/j.cnki.cyxb.2010.01.041.
Objective:To investigate the expression and the clinical significance of survivin in renal clear cell carcinoma 786-O.Methods:The expression of survivin mRNA and protein were detected by RT-PCR and immunohistochemisty
The growth curve of renal clear cell carcinoma 786-O were detected by MTT.Results:The survivin mRNA and protein were detected in 786-O cells.In contrast
no expression of survivin was found in normal renal cells.Conclusion:The survivin gene and protein were significantly expressed in renal clear cell carcinoma 786-O.This may provide the experimental evidence for the survivin gene as a target of gene therapy in renal cancer.