Objective:To observe the memory functional change in patients with epilepsy after anterior temporal lobectomy

andtoanalyze the influencing factors.Methods:48 patients with epilepsy undergoing anterior temporal lobectomy were enroll in this study

and followed up for 1 year.Clinical Memory Scale was used to assess the memory function at 1 week before operation

2nd week and the 6th month after the operation

respectively.Results:In the 1 year follow-up

38 patients were graded as Engle I

6 patients

as Engle Ⅱ

3 patients

as Engle Ⅲ

and 1 patients as Engle Ⅳ.Two weeks after operation

the memory function in patients significantly reduced;six months after operation

the memory function resorted

to the same level as that 1 week before operation.And patients with hippocampal sclerosis

operation at dominant hemisphere side

and the poor prognosis had more noticeable memory function decline.Conclusion:The memory function decline at 2 weeks after anterior temporal lobectomy for patients with epilepsy

then restored gradually.Hippocampal sclerosis

operation at dominant hemisphere side

poor prognosis may be the risk factors.