QIN Fen, et al. Proteomic analysis of serum from patients with polycystic ovary syndrome[J]. Journal of Chongqing Medical University, 2010,35(1):22-24.
QIN Fen, et al. Proteomic analysis of serum from patients with polycystic ovary syndrome[J]. Journal of Chongqing Medical University, 2010,35(1):22-24. DOI: 10.13406/j.cnki.cyxb.2010.01.025.
Objective:To find out disease specific-proteins(DSPs)which are closely collelated with Polycystic ovary syndrome.Methods:proteins ext racted from serum were run in immobilized pH gradient isoelectic focusing(IPG-IEF)at the first dimension.The proteins pots in gels were visuali zed by silver staining protocol followed by gel scanning and analysised by Pdquest 7.3 software.The differentially displayed protein spot s were searched and identifiyed by MALDI-T0F-MS.spots associated with PCOS.Results:Two DSPs were found and they were apolipoprotein A-I
Heat shock protein 70.Conclusion:There were different protein expressing in 2D-PAGE of Polycystic ovary syndrome and control group.These proteins may be DSPs of Polycystic ovary syndrome.