Objective:to investigate the status ofpatients with genitourinarytract infection caused byUreaplasma urealyticum(Uu)and Mycoplasma hominis(Mh)

and its drug susceptibility and resistance in Chongqing.Methods:The genitourinary tract samples from 8 494 doubtful patients with mycoplasma infection were cultured and the susceptibility of the disease to 10 routine antibiotics was measured by mycoplasma cultivation

identification and drug susceptibility integration kit.Results:In the results of mycoplasma cultivation of 8 494 doubtful cases

2 735 cases were positive(32.2%)

and 2 239 of them were simple Uu infection(26.4%)

and 29 cases were simple Mh infection(0.3%)and 467 cases were double infection(5.5%).The results ofsusceptibilitytest showed that the sensitivityofUu toMinocycline

Deoxycycline

Clarithromycin

Azithromycin

JosamycinandRoxithromycinwas96.4%

95.4%

94.4%

87.1%

74.2%

and 73.3%

respectively

but tospectinomycin was 6.5%.Otherwise

the sensitivityofMh toDeoxycycline

Minocycline

Josamycin and Lincomycin was 100%

96.6%

96.6%

86.2% respectively

but toRoxithromycin

Azithromycin

Clarithromycin was 0%

0%

3.4% respectively.The double infection was the most sensitive to Minocycline and Deoxycycline

then to Josamycin

and the sensitivity was 92.1%

89.7% and 61.2%

respectively

but the sensitivityofittoRoxithromycin

Azithromycin

Clarithromycin

andSpectinomycinwas3.9%

5.2%

8.6%

and9.4%respectively.Conclusion:Mycoplasma is one of the main pathogen in genitourinary tract non-gonococcus inflammation

especially Uu infection.The therapy of mycoplasma infection should depress the production ofdrugresistant strain bythe reasonable adoption ofantibiotics accordingtothe results of susceptibilitytest.