JIA Yongcun, et al. Expression of HOXa-10 gene in endometrium mice during early pregnancy[J]. Journal of Chongqing Medical University, 2007,(12):1260-1264.
JIA Yongcun, et al. Expression of HOXa-10 gene in endometrium mice during early pregnancy[J]. Journal of Chongqing Medical University, 2007,(12):1260-1264. DOI: 10.13406/j.cnki.cyxb.2007.12.013.
Objective:To investigate the effect of HOXa-10 gene in the mouse uterus during embryo implantation. Method: real-time fluorescence quantitative PCR (FQ-PCR) and immunohistochemistry were used to detect the HOXa-10 gene and protein of the mouse of un-pregnant pregnant d1
d2
d3
d4
d5 and d7. Result:The HOXa-10 mRNA/β-actin mRNA expression in pregnant group is higher than that of non-pregnant grnup
and the results showed gradual hoist trend as days past
the HOXa-10 mRNA expression reached the maximum at pregnant d4. Immunohistochemical analysis showed the same results as FQ-PCR. Conclusion:HOXa-10 is persistently expressed in mouse endometrium during the early pregnancy and maybe participates in the regulation process of mouse blastodyst implantation.