Objective:To study the general pharmacological actions of bencycloquidium bromide.Methods:Bencycloquidium bro- mide was administered through nasal mucosa in high

medium and low doses to mice and beagle dogs.The psycho-nervous action

enraging response

voluntary movement

bronchus gland excretion

small intestine peristalsis of mice were observed

and the cardiovascular and respiratory reactions of beagle dogs were detected.Results:Bencycloquidium bromide had no obvious effect on cardiovascular and respiratory systems of beagle dogs;but it had inhibitory action on central nerve system of mice which can be relieved later.It could also decrease the excretion of bronchus gland and the peristalsis of small intestine.Conclusion:Bencycloquidium bromide had no obvious effect on cardiovascular system and respiratory system in animals;but had certain inhibitory action on central nerve system

and could decrease the excretion of bronchus gland and inhibit the peristalsis of small intestine in animals.