ZHONG Jiarong et al. Comparison of the drugs used for cardioversion of paroxysmal supra - ventricular tachycardia in children: 40 cases[J]. Journal of Chongqing Medical University, 2005,(6):895-898.
ZHONG Jiarong et al. Comparison of the drugs used for cardioversion of paroxysmal supra - ventricular tachycardia in children: 40 cases[J]. Journal of Chongqing Medical University, 2005,(6):895-898. DOI: 10.13406/j.cnki.cyxb.2005.06.035.
Objective;To compare and assess the curative effects
starting time and side effects of cardioversion drugs used for treatment of paroxysmal supra - ventricular tachycardia ( PSVT)
including adenosine triphosphate ( ATP)
dofetilide
and cedilanid. Methods; The data of 40 admitted children with PSVT treated with ATP
dofetilide and cedilanid in recent 5 years were collected. The cardioversion time
success rate and side effects of the drugs were compared. The constituent ratio was determined with check x2. Significant level a was 0.05. Results: In group ATP
89.47% of patients were interrupted; 63. 15% of them had side effects; the cardioversion time of ATP was 3-30 seconds. In group dofetilide
72.73% the patients were interrupted; 9.09% of them had side effects; the cardioversion time of dofetilide was 5- 30min. In group cedilanid
61. 11% the patients were interrupted; 5. 55% of them had side effects; the cardioversion time of dofetilide was 20min -5h. Conclusion; ATP should be considered the drug of first choice for PSVT in children without organic heart diseases and serious complication and it has only minor and transient side effects. Dofetilide is equally effective in interrupting PSVT
and has minor side effects
which should be considered the first choice and best suitable for atrioventric-ular reentrant tachycardia. Cedilanid should be considered the drug of first choice for PSVT in children with serious heart failure
and it has a synergic effect to ATP and dofetilide.
关键词
阵发性室上性心动过速药物复律小儿
Keywords
Paroxysmal supra - ventricular tachycardiaCardioversionchildren