Objective; To discuss the related factors of Surgical Intensive Care Unit in order to further reduce the death rate in SICU. Methods; The clinical data of 112 death cases were analyzed retrospectively. Results; The dead cases in the SICU had certain features. The high MODS incidence and unsolved surgical problems should be paid attention to so as to prevent errors during the treatment process actively. Conclusion; The recognition of surgical critical illness and the special knowledge should be enhanced so as to improve the cure successful rate of SICU.