异基因外周血干细胞移植治疗以急性淋巴细胞白血病起始的慢粒急淋变1例

娄世锋; 陈林; 陈姝; 周慷; 罗云; 邓建川

doi:10.13406/j.cnki.cyxb.2005.03.049

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异基因外周血干细胞移植治疗以急性淋巴细胞白血病起始的慢粒急淋变1例

更新时间：2024-01-17

- 异基因外周血干细胞移植治疗以急性淋巴细胞白血病起始的慢粒急淋变1例
- AIIo-peripheral blood stem cell transplantation was performed to a case of lymphocytic blast crisis of chronic myeloid leukemia at the onset of acute lymphocytic leukemia
- 重庆医科大学学报 2005年第3期页码：472-474
- 作者机构：
  
  1. 重庆医科大学第二临床学院血液科
  2. 重庆医科大学第二临床学院血液科,重庆,400010
- 作者简介：
- 基金信息：
  
  重庆市科委科研基金支持项目,渝科发计字200152
- DOI：10.13406/j.cnki.cyxb.2005.03.049
  中图分类号： R733.7
- 纸质出版日期：2005，
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[1]娄世锋,陈林,陈姝,周慷,罗云,邓建川.异基因外周血干细胞移植治疗以急性淋巴细胞白血病起始的慢粒急淋变1例[J].重庆医科大学学报,2005(03):472-474.

LOU Shifeng, et al. AIIo-peripheral blood stem cell transplantation was performed to a case of lymphocytic blast crisis of chronic myeloid leukemia at the onset of acute lymphocytic leukemia[J]. Journal of Chongqing Medical University, 2005,(3):472-474.
[1]娄世锋,陈林,陈姝,周慷,罗云,邓建川.异基因外周血干细胞移植治疗以急性淋巴细胞白血病起始的慢粒急淋变1例[J].重庆医科大学学报,2005(03):472-474. DOI： 10.13406/j.cnki.cyxb.2005.03.049.

LOU Shifeng, et al. AIIo-peripheral blood stem cell transplantation was performed to a case of lymphocytic blast crisis of chronic myeloid leukemia at the onset of acute lymphocytic leukemia[J]. Journal of Chongqing Medical University, 2005,(3):472-474. DOI： 10.13406/j.cnki.cyxb.2005.03.049.

摘要

目的:观察无血缘关系异基因外周血干细胞移植对以急性淋巴细胞白血病（ALL）起始的儿童慢性粒细胞白血病急淋变的治疗效果。方法:对以ALL起始的慢性粒细胞白血病急淋变患儿行无血缘关系异基因外周血干细胞移植术。结果:+17天开始恢复造血（WBC0.6×109/L>0.5×109/L）

+22天血小板>20×109/L

+30天骨髓示正常增生性骨髓象

PH（-）

无病生存>110天。结论:无血缘关系异基因外周血干细胞移植术对以急性淋巴细胞白血病（ALL）起始的儿童慢性粒细胞白血病急淋变有较好疗效。

Abstract

Objective:To observe the efficacy of allo-peripheral blood stem cell transplantation performed to a case of lymphocytic blast crisis of chronic myeloid leukemia at the onset of acute lymphocytic leukemia.Methods:The patient was treated with allo-peripheral blood stem cell transplantation from HLA-matched unrelated donor.Results:Haematopoiesis was reconstructed by donor stem cell after 30 days

ph chromosome has been negative from then.The patient is desease free survival more than 110 days.Conclusion:[WTBZ]Allo-peripheral blood stem cell transplantation is effective to lymphocytic blast crisis of chronic myeloid leukemia at the onset of acute lymphocytic leukemia.

关键词

急性淋巴细胞白血病慢性粒细胞白血病急淋变外周血干细胞移植异基因

Keywords

Acute lymphocytic leukemiaChronic myeloid leukemiaLymphoblastic crisisAllo-peripheral blood stem cell transplantationXenogenetic

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