Objective:To observe the phenomena of lens regeneration in rabbits in vivo and the influence of vitamin A on it.Methods:Intracapsular lens extraction were done.Following the operation

0.1ml vitamin A oil was given by subcutaneous injection into abdomen every other day in experimental group

while 0.1ml saline was given in control group.This procedure lasted 2 months.The animals were observed regularly after operation and were put to death at the 16th week follwing the operation.The state of lens regeneration were analyzed by means of tissue sections and ultrathin sections.Results:There were 3 and 1 eye(s)in which regenerated lens-like substance was found in the back of iris respectively in experimental group and in control group.The regenerated substance was estimated to be typical lens sturcture after the light microscopical and electron microscopical analysis.Conclusion:Our experiment suggests that the substance possessing typical lens structure can be regenerated after lens extraction in rabbit

although the intact regenerated lens is not found at present.Vitamin A can accelerate this course in vivo.