LUO Shifang, et al. A study on the relationship between the plasma level of AVP and brain water content after severe burn in rats[J]. Journal of Chongqing Medical University, 2005,(2):246-248.
LUO Shifang, et al. A study on the relationship between the plasma level of AVP and brain water content after severe burn in rats[J]. Journal of Chongqing Medical University, 2005,(2):246-248. DOI: 10.13406/j.cnki.cyxb.2005.02.023.
Objective:To investigate the relationship between the dynamic plasma level of arginine-vasopressin (AVP) and the brain water content (BWC) in the rats after severe burn.Methods:Radioimmunoassay(RIA) was performed to measure the dynamic plasma levels of AVP in the rats.Dry-wet weight method was used to measure the changes of water content in brain.All the data were statistically processed.Results:The plasma level of AVP and BWC in the rats increased after severe burn
and the plasma level reached the peak at 6h after burn.The positive correlations were observed between the two parameters( r =0.8790
P <0.01).Conclusion:The results suggest that the plasma level of AVP might reflect the severity of brain edema after severe burn.
关键词
严重烧伤AVP含水量大鼠
Keywords
Severe burnArginine-vasopressinBrain water contentrat