Objective:To investigate the relationship among serum uric acid

C-reactive protein and the degree of carotid artery atherosclerosis in patients with essential hypetension.Methods:122 patients with essential hypertension were divided into intima-media thickness group(Ⅰ)

plaque development group(Ⅱ) and vessel stenosis group(Ⅲ).Concentration of serum uric acid and C-reactive protein were measured in each patient and the relationship between serum uric acid and C-reactive protein was observed.Results:The concentrations of serum uric acid and C-reactive protein in group Ⅱ and Ⅲ were positively connected with pathologic changes of carotid artery atherosclerosis( P <0.05).The concentration of serum uric acid had a positive relation to that of C-reactive protein( r =0.45

P <0.01).Conclusion:The concentrations of serum uric acid and C-reactive protein have a positive relation to the degree of carotid artery atherosclerosis.