GUO Shuquan, et al. Study of augmenter of liver regeneration in rat testis[J]. Journal of Chongqing Medical University, 2005,(1):39-41. DOI: 10.13406/j.cnki.cyxb.2005.01.011.
Objective:To confirm the expression and localization of augmenter of liver regeneration(ALR) in baby
mature and the old rat testis and to evaluate the function of ALR in reproduction.Methods:ALR expression and localization in baby
mature and the old rat testis were examined by immunohistochemistry
ALR expressions of the mature rat testis and liver were examined in 12h
24h and 48h after 70 percent partial hepatectomy(PH) as well.Results:ALR was expressed in the cytoplasm and membrane of cells and it commonly existed in Leydig cells
Sertoli cells and sperm cells of rat testis
especially in spermatogonia and spermatocytes.ALR expressions differed among baby
mature and the old rat testis
in the way from the strongest to the weakest.After 70 percent PH ALR expression increased in liver
peaking in 24h
while that in testis didn’t change.Conclusion:ALR expression in testis is strong which is necessary for testis development
spermatogenesis and mature sperm.The function of ALR is organ special.