原发性单纯收缩期高血压患者自主神经活性及其昼夜节律

邓昌明; 黄晶; 罗开良; 殷跃辉

doi:10.13406/j.cnki.cyxb.2004.05.034

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原发性单纯收缩期高血压患者自主神经活性及其昼夜节律

更新时间：2024-01-17

- 原发性单纯收缩期高血压患者自主神经活性及其昼夜节律
- A study on heart rate variability and its circadian rhythm of patients with isolated systolic hypertension
- 重庆医科大学学报 2004年第5期页码：675-676
- 作者机构：
  
  1. 重庆医科大学第二临床学院心血管内科
  2. 重庆医科大学第二临床学院心血管内科,重庆,400010
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2004.05.034
  中图分类号： R544.1
- 纸质出版日期：2004，
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[1]邓昌明,黄晶,罗开良,殷跃辉.原发性单纯收缩期高血压患者自主神经活性及其昼夜节律[J].重庆医科大学学报,2004(05):675-676+681.

DENG Changming, et al. A study on heart rate variability and its circadian rhythm of patients with isolated systolic hypertension[J]. Journal of Chongqing Medical University, 2004,(5):675-676.
[1]邓昌明,黄晶,罗开良,殷跃辉.原发性单纯收缩期高血压患者自主神经活性及其昼夜节律[J].重庆医科大学学报,2004(05):675-676+681. DOI： 10.13406/j.cnki.cyxb.2004.05.034.

DENG Changming, et al. A study on heart rate variability and its circadian rhythm of patients with isolated systolic hypertension[J]. Journal of Chongqing Medical University, 2004,(5):675-676. DOI： 10.13406/j.cnki.cyxb.2004.05.034.

摘要

目的 :探讨原发性单纯收缩期高血压患者自主神经活性及其昼夜节律变化。方法 :对 92例原发性单纯收缩期高血压患者进行 2 4h及每小时心率变异时域分析

并与年龄匹配的对照组比较

同时比较高血压伴与不伴左心室肥厚者心率变异及其昼夜节律。结果 :原发性单纯收缩期高血压患者时域分析各项指标均下降（P <0 .0 1）

高血压伴左心室肥厚组rMSSD、pNN5 0进一步降低（P <0 .0 1）

昼夜节律消失。结论 :原发性单纯收缩期高血压患者心率变异减低

自主神经功能受损

平衡失调。高血压伴左心室肥厚者迷走神经功能进一步受损

昼夜节律消失

Abstract

Objective:To investigate heart rate variability(HRV)and its circadian rhythm of patients with isolated systolic hypertension.Methods:HRV was evaluated by using 24-hour Holter monitoring in 92 isolated systolic hypertensive patients

and compared with age-matched normal controls.Furthermore

HRV and its circadian rhythm were evaluated in two subgroups with and without left ventricular hypertrophy(LVH).Results:All HRV time domain index were lower among patients than normal controls.As compared with the patients with and without LVH

rMSSD and pNN50 were significantly decreased in patients with LVH.The circadian rhythm was blunted in patients without LVH

but it was absent in patients with LVH.Conclusion:Our results suggest that HRV is decreased in isolated systolic hypertensive patients.Parasympathetic tone is lower in patients with LVH than those without LVH

and the sympathetic/parasympathetic tone is altered.

关键词

原发性单纯收缩期高压血左心室肥厚心率变异昼夜节律

Keywords

Isolated systolic hypertensionleft ventricular hypertrophyheart rate variabilityCircadian rhythm

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