WU Qingchen, et al. Diagnosis and management of the syndrome of inappropriate secretion of antidiuretic hormone after thoracotomy[J]. Journal of Chongqing Medical University, 2004,(4):544-545.
WU Qingchen, et al. Diagnosis and management of the syndrome of inappropriate secretion of antidiuretic hormone after thoracotomy[J]. Journal of Chongqing Medical University, 2004,(4):544-545. DOI: 10.13406/j.cnki.cyxb.2004.04.046.
Objective:To explore the diagnosis and management of the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) after thoracotomy.Methods:The clinical data of three patients with SIADH after thoracotomy (1 radical operation of esophageal carcinoma
1 radical operation of cardia carcinoma
1 pulmonary lobectomy) were analyzed retrospectively.Results:All 3 patients were males with an average age of 71.4(67.5~74)years.Psychiatric symptoms (the state of delirium) were manifestated by all patients during 3rd to 4th day after thoracotomy
and meanwhile their serum sodium decreased significantly(125~126mmol/L);urine sodium increased abnormally(74.9~101 mmol/L);plasma osmolality decreased(255~280mosm/kg H
2
O) and osmolality of urine rised(540~695mosm/kg H
2
O).The psychiatric symptoms of 3 patients disappeared and their serum sodium
urine sodium
plasma osmolality
osmolality of urine reversed to normal after water restriction(800~1000ml/24h) for 4 to 6 days.Conclusion:The causes of SIADH after thoracotomy may be related to positive pressure respiration