TANG Xiaonin, et al. Analgesic effect of different concentration of ropivacaine/fentanyl for postoperative patient-controlled epidural analgesia[J]. Journal of Chongqing Medical University, 2004,(3):354-355.
TANG Xiaonin, et al. Analgesic effect of different concentration of ropivacaine/fentanyl for postoperative patient-controlled epidural analgesia[J]. Journal of Chongqing Medical University, 2004,(3):354-355. DOI: 10.13406/j.cnki.cyxb.2004.03.032.
Objective:To compare the analgesic and side effect of patient-controlled epidural analgesia with two different solutions of ropivacaine/fentanyl after hysterectomy.Methods:Forty ASA Ⅰ-Ⅱ patient undergoing elective hysterectomy under epidural anesthesia were randomly divided into two groups:0.15% ropivacaine- 2μg/ml fentany group (R 1
n =20) and 0.2% ropivacaine-2 μg/ml fentanyl group (R 2
n =20).Patient- controlled epidural analgesia setting for the two solutions:the loadinding doses was 6ml
bolus dose was 5ml
lock-out interval time 20 min and maximal amount within 4 h was 40ml in both groups.The clinical effects were assessed by(1)VAS score of pain (0=no pain
10=severe pain)
(2)modified Bromage score
(3)monitoring heart rate and blood pressure after preoperation and analgesia
(4)the time when the patient passed gas and(5)side effect (nausea
vomiting
motor block et al).Results:All two solutions produced equivalent analgesia.Motor block was significantly more common and more intense with the 0.2% ropivacaine-2μg fentanyl solution.Other side effects were equivalent between solutions and mild. Conclution:Our results suggest that 0.15% ropivacaine -2μg fentanyl solution for postoperative PCEA after lower abdominal surgery provides satisfactory analgesia and less motor block.