Objective:To discuss the effects and limitation of neuronavigation system in neurosurgical operations.Methods:58 cases surgically treated with Stealth Station 4.1 Neuronavigation System were analysed

including 52 cases of intracranial tumor

4 cases of cerebral vascular malformations and 2 cases of intracerebral abscess. The locations of lesion included superficial part of hemisphere (24 cases)

deep part of hemisphere (21 cases)

skull base (8 cases)

cerebellum (2 cases) and brain stem (3 cases).Results:Among 58 cases

total removal of the lesion was performed on 45 cases

comprising 77.6%

subtotal removal on 5

comprising 8.6%

most removal on 2%

comprising 3.4% and partial removal on 6%

comprising 10.3%.Postoperative neurological functions were improved or remained unchanged in 52 cases while they were worsened in 5 cases

and 1 patient died.Conclusion:Neuronavigation system is safe and helpful for improving accuracy of neurosurgical operations and increasing total removal of lesions

and it can be used widely in neurosurgery. However

it can’t avoid intraoperative brain shift.The effects of navigation system in different neurosurgical operations are evaluated.