Objective:To explore the risk factors for laparoscopic cholecystectomy (LC) for acute cholecystitis.Methods:The LC clinical data on 153 patients with acute cholecystitis were summarized and analyzed by stepwise logistic regression(forward).Results:It was found that among the 153 cases of acute cholecystitis

125 underwent laparoscopic cholecystectomy successfully and 28(18.30%) had conversion to open cholecystectomy.The risk factors for unsuccessful LC in acute cholecystitis included previous upper abdominal operation or recurrence history

rigidity in right upper abdomen

leukocytosis

stone incarceration on the neck of the gallbladder and no visualization of the gallbladder sonographically

more than 72 hours of onset of symptomatic cholelithiasis.In addition

conversion to open cholecystectomy should be made unconditionally

once intensive dense adhesion and unclear discrimination of Calot′s triangle happened for the duration of LC.Conclusion:The risk score for LC in acute cholecystitis in the study is helpful for evaluating completely the patients of LC before operation

and for increasing success rate and decreasing complication incidence of LC.