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1. 重庆医科大学临床学院烧伤整形科
2. 重庆医科大学临床学院烧伤整形科,重庆,400016
纸质出版日期:2004,
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[1]杨天荣,薛斌,贺光照,黄崇本.预缝合皮肤伸展术生物力学、组织学研究[J].重庆医科大学学报,2004(01):66-70.
YANG Tianrong, et al. Study on the biomechanic and histological changes of skin extended by presuturing in piglets and its clinical application[J]. Journal of Chongqing Medical University, 2004,(1):66-70.
[1]杨天荣,薛斌,贺光照,黄崇本.预缝合皮肤伸展术生物力学、组织学研究[J].重庆医科大学学报,2004(01):66-70. DOI: 10.13406/j.cnki.cyxb.2004.01.021.
YANG Tianrong, et al. Study on the biomechanic and histological changes of skin extended by presuturing in piglets and its clinical application[J]. Journal of Chongqing Medical University, 2004,(1):66-70. DOI: 10.13406/j.cnki.cyxb.2004.01.021.
目的 :探讨预缝合皮肤伸展术的生物力学及组织学改变
为临床应用提供实验依据。方法 :选择白色乳猪为实验动物。检测伸展面积、组织学改变
皮肤的应力—应变及切口抗裂开强度等。结果 :直接预缝合皮肤伸展术后随时间增而皮肤面积增加、长度延伸 ;皮肤厚度变薄 ;距牵引缘 1~ 2cm扩展面积最明显
被牵引区成纤维细胞粗面内质网有空泡样改变 ;皮肤张力随时间延长逐渐减小。结论 :预缝合术后
扩展皮肤来源主要涉及周围组织移位、邻近牵引缘皮肤扩张和组织增生 ;伸展皮肤主要涉及距牵引缘约 5cm左右范围 ;其伤口抗张力强度未降低
可以在修复皮肤缺损方面推广应用。
Objective:To probe into the changes of skin extended by presuturing in respect to biomechanic alteration
source of extended skin
scope of skin involved in extension and histological changes to provide an experimental basis for clinical application.Methods:The white piglet was adopted as animal model.The parameters observed were as follows:area of extra skin obtained histolgical changes
stress-stain relation of skin under stretch
anti-tensile.Results:The results showed that at 24hr
45hr and 72hr after presuturing
the areas of skin extended
and the length of skin were increased.The thickness of epidermis and dermis of stretched skin were thinner.The area with maximum extension was located in 1~2 cm away from stretching borders.The electron microscopic observation showed that in the rough endoplasmic reticulum of fibroblasts
vacuolar degeneration could be seen.Stress-strain relation showed that extensile force decreased with the passage of time.Conclusion:①Stress-stain relation shows that extensile force decreases with the passage of time.②The sources of extended skin include:the displacement of adjacent tissue and the extension of stretched skin and the proliferation of tissue.③The area affected by stretching is mainly limited within 5cm adjacent to stretching border.④The anti-tensile strength of healing wound of extended skin is the same as that of normal skin.
皮肤伸展术预缝合生物力学组织学
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