Objective:To review the X-ray manifestations of the skeletal lesions in children with Langerhans cell histocytosis(LCH)

and to evaluate the X-ray examination in the diagnosis of LCH.Methods:The skeletal plain films of 35 children with LCH were analysed retrospectively.AⅡ cases were confirmed by pathology.Results:Among 35 cases

skull destructions were found in 24(68.6%)

vertebral destruction in 8(22.9%)

long bone destruction in 12(34.3%)

flat bone and irregular bone destruction in 4(11.4%).Eosinophilic granulomas mainly involved skull

vertefra and long bones

while Letterer-Siwes disease

Hand-Schuller-Christian disease and intermediary type mainly involved skull bones.Conclusion:Multilocation

diversity and changeability of the skeletal lesions are the x-ray features of LCH in children.X-ray examination and follow-up play an important role in the diagnosis of LCH.