Objective:To determine the influence of STOP(suction termination of pregnancy) with propofol anesthesia on stress hormone in the patients.Methods:Early pregnant patients of ASA Ⅰ-Ⅱ grade were divided randomly into two groups.The group C( n =32)

as control group

received no anesthetic agent during STOP.The group P( n =34) was intervened with propofol anesthesia.BP

HR

So 2% were measured continuously during STOP.Blood samples were obtained from 66 patients at the following intervals:before STOP and 5min after STOP

and the plasma cortisol

blood sugar

insulin

C-peptide and growth hormone levels were measured.Results:The BP and HR decreased significantly during STOP and after STOP in group C compared with group P.The cortisol level in group C increased obviously aftr STOP.The significant difference in cortisol level was observed between two groups.Conclusion:STOP under propofol anesthesia could avoid the harm from the STOP syndrome and would not disturb the endocrine system of the patients.