PENG Dongtao, et al. Expression significance of MMP9,MMP2 and PCNA in transitional cell carcinoma of bladder[J]. Journal of Chongqing Medical University, 2003,(4):467-469.
PENG Dongtao, et al. Expression significance of MMP9,MMP2 and PCNA in transitional cell carcinoma of bladder[J]. Journal of Chongqing Medical University, 2003,(4):467-469. DOI: 10.13406/j.cnki.cyxb.2003.04.018.
Objective:To study the expression and clinical significance of matrix metalloproteinase(MMP9
MMP2)in transitional cell carcinoma of bladder(TCCB).Methods:Applying S-P immunohistochemical technique
expression of MMP9 and MMP2 was studied in 64 TCCB.Results:There was 60.93%(39/64) with MMP9 and 42.19%(27/64) with MMP2 expression.There was a significant correlation between MMP9 expression and PCNA
pathological grade
clinical stage
tumor size.However
the relationship had not been found with patient age
sex as well as the number of tumor.Conclusion:MMP9 appears to be an independent biological marker for predicting prognosis and comprehensive treatment of TCCB.