Objective:Endoscopic retrograde cholangiopancreatography (ERCP) and sphincterotomy (EST) are well accepted as the procedure of choice for diagnostic and therapeutic purposes of pancreaticobiliary disease. The aim of this study is to investigate the curative effect and complication of pancreaticobiliary disease managed by therapeutic ERCP. Methods: A total of 59 patients with common bile duct stone

acute obstructive suppurative cholangitis

malignant bile duct obstruction

acute or chronic pancreatitis

and sphincter of Oddi dysfunction. Each case was confirmed by ultrasonographic examination

diagnostic ERCP and blood amylase test. All patients underwent therapeutic ERCP such as EST

stone extraction and drainage. Results :Of the 59 patients

16 patients with acute obstructive suppurative cholangitis and severe acute pancreatitis underwent urgent management of endoscopic intervention

stone extraction and endoscopic nasobiliary drainage. The remaining 43 patients underwent diagnostic ERCP

followed by therapeutic ERCP in cases of documented bile duct stone

sphincter of Oddi dysfunciton

or chronic pancreatitis. The success rate of endoscopic procedure was 100%

and the complication rate was 6. 8%

without mortality. Conclusion : In patients with pancreaticobiliary disease

therapeutic ERCP provides adequate management and is associated with low complication rates.