ZHONG Qing, et al. The level and the clinical significance of anticardiolipin antibodies in patients with lupus nephritis[J]. Journal of Chongqing Medical University, 2003,(1):11-13.
ZHONG Qing, et al. The level and the clinical significance of anticardiolipin antibodies in patients with lupus nephritis[J]. Journal of Chongqing Medical University, 2003,(1):11-13. DOI: 10.13406/j.cnki.cyxb.2003.01.004.
Objective :To study the significance of anticardiolipin antibodies (ACA) in patients with lupus nephritis( LN). Methods : We detected serum ACA in 32 cases of LN. The control group consisted of 28 healthy cases. We observed the relation between the levels of ACA and the levels of clinical biochemical index. Results :The positive rate of IgG- ACA
IgM- ACA IgA- ACA was 53. 1%
40. 6%
46. 9% in patients with LN. In patients with positive ACA
lower levels of hemoglobin
thrombocytopeinia and C3 were observed as well as elevated levels of serum IgG
24h- urine protein
antinuclear antibody titer and serum creatinine(P<0.05). Conclu-sion: The patients with positive ACA may be accompanied with more severe immunolgical function disorder
higher hypercoagulable state and impairment of renal function.
关键词
抗心磷脂抗体狼疮性肾炎免疫功能高凝状态
Keywords
Anlicardiolipin antibodieslupus nephritisHypercoagulability stateImmunological function