Objective: To improve the diagnosis and treatment level and to decrease the mortality of neonatal gastrointestinal perforation. Methods: To analyse thirty-three cases of neonatal gastrointestinal perforation from 1991to 1999. Twenty-two boys and eleven girls are retrospected. Among them

thirteen are perforation of NEC

nine are gastric perforation

two are congenital megacolon accompanying colonic perforation of colitis

one is cecum perforation.Two are Meckels diverticulitis perforation and two due to perforation of intestinal atresia respectively. Perforation of incarcerated hernia after reposition is found in one case. Three are unknown for the cause of perforation. Results: The cure rate is 54.5%

mortality rate is 33.3%(10/33)

and five out of thirty-three were given up for treatment. Conclusion: The key to decrease the mortality is early diagnosis

perioperation treatment and operation.