血清唾液酸测定对口腔颌面部肿瘤诊断及疗效观察的意义

张福军; 季平; 陈睿; 唐鹏

doi:10.13406/j.cnki.cyxb.2002.01.025

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血清唾液酸测定对口腔颌面部肿瘤诊断及疗效观察的意义

更新时间：2024-01-17

- 血清唾液酸测定对口腔颌面部肿瘤诊断及疗效观察的意义
- Clinical significance of determination of serum sialic acid in patients with oral and maxillofacial tumors
- 重庆医科大学学报 2002年第1期页码：76-78
- 作者机构：
  
  1. 重庆医科大学临床学院口腔科
  2. 重庆医科大学临床学院口腔科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2002.01.025
  中图分类号： R739.8
- 纸质出版日期：2002，
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[1]张福军,季平,陈睿,唐鹏.血清唾液酸测定对口腔颌面部肿瘤诊断及疗效观察的意义[J].重庆医科大学学报,2002(01):76-78.

ZHANG Fujun, et al. Clinical significance of determination of serum sialic acid in patients with oral and maxillofacial tumors[J]. Journal of Chongqing Medical University, 2002,(1):76-78.
[1]张福军,季平,陈睿,唐鹏.血清唾液酸测定对口腔颌面部肿瘤诊断及疗效观察的意义[J].重庆医科大学学报,2002(01):76-78. DOI： 10.13406/j.cnki.cyxb.2002.01.025.

ZHANG Fujun, et al. Clinical significance of determination of serum sialic acid in patients with oral and maxillofacial tumors[J]. Journal of Chongqing Medical University, 2002,(1):76-78. DOI： 10.13406/j.cnki.cyxb.2002.01.025.

摘要

目的：　探讨血清唾液酸（ＳＡ）检测对口腔颌面部肿瘤诊断及疗效观察的应用价值。方法：　对１５１例血清标本进行了唾液酸（ＳＡ）的检测。结果：恶性肿瘤组血清ＳＡ含量明显高于正常对照组和良性肿瘤组（ｑ　＝１８．７５～２１．０４，　Ｐ　＜０．０１）；　恶性肿瘤组经手术及化疗等治疗显效者，血清ＳＡ水平显著下降（ｔ　＝９．８０～３５．３５，　Ｐ　＜０．０１），但仍高于正常组（ｔ　＝７．２０，　Ｐ　＜０．０１）；ＳＡ水平持续保持在高水平甚至上升则预后较差。结论：　血清ＳＡ测定对口腔颌面部肿瘤诊断及疗效观察有一定的参考价值。

Abstract

Objective: To study the use of determination of serum sialic acid in diagnoses and curative effect observation of oral and maxillofacial tumors. Methods: The contents of SA of 151 samples including 60 normal persons

53 benign and 38 malignant oral-facial tumors were determined. Results:The contents of serum SA of the patients with malignant tumors were significantly higher than that of normal persons and the patients with benign tumors (q =18.75～21.04

P<0.01). The contents of serum SA of the patients with malignant tumors were significantly decreased when the therapy (including operation and chemotherapy) was effective(t =9.80～35.35

P<0.01)

but were still higher than that of normal persons（t =7.20

P<0.01）. On the contrary

the contents of serum SA remained high or even higher when the malignant tumors recurred or metastasized. Conclusion: Determination of serum SA was valuable in diagnoses and curative effect observation of oral and maxillofacial tumors.

关键词

血清唾液酸肿瘤诊断疗效观察

Keywords

Sialic acidtumorDiagnosesCurative effect observation

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