术后并发严重盛染患者血清E-选择素、IL-10和sCD<sub>14</sub>的变化及其与预后的关系

杨镛; 杨国凯; 罗开元

doi:10.13406/j.cnki.cyxb.2001.04.026

您当前的位置：

首页 >

文章列表页 >

术后并发严重盛染患者血清E-选择素、IL-10和sCD₁₄的变化及其与预后的关系

更新时间：2024-01-17

- 术后并发严重盛染患者血清E-选择素、IL-10和sCD₁₄的变化及其与预后的关系
- Dynamics of levels of E - selectin, interleukin - 10 and soluble CD14 in serum of pateints complicating severe infection
- 重庆医科大学学报 2001年第4期页码：439-442
- 作者机构：
  
  1. 重庆医科大学临床学院外科
  2. 云南省第二人民医院普外科,重庆,400016
  3. ,昆明
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2001.04.026
  中图分类号： R619
- 纸质出版日期：2001，
扫描看全文
[1]杨镛,杨国凯,罗开元.术后并发严重盛染患者血清E-选择素、IL-10和sCD_(14)的变化及其与预后的关系[J].重庆医科大学学报,2001(04):439-442.

YANG Yong, et al. Dynamics of levels of E - selectin, interleukin - 10 and soluble CD14 in serum of pateints complicating severe infection[J]. Journal of Chongqing Medical University, 2001,(4):439-442.
[1]杨镛,杨国凯,罗开元.术后并发严重盛染患者血清E-选择素、IL-10和sCD_(14)的变化及其与预后的关系[J].重庆医科大学学报,2001(04):439-442. DOI： 10.13406/j.cnki.cyxb.2001.04.026.

YANG Yong, et al. Dynamics of levels of E - selectin, interleukin - 10 and soluble CD14 in serum of pateints complicating severe infection[J]. Journal of Chongqing Medical University, 2001,(4):439-442. DOI： 10.13406/j.cnki.cyxb.2001.04.026.

摘要

目的：探讨术后并发严重感染病人血清Ｅ-选择素（Ｅ－ＳＬＴ）、白细胞介素－１０（ＩＬ－１０）和可溶性ＣＤ１４（ｓＣＤ１４）的变化情况及其与病情预后的关系。方法：采用ＥＬＩＳＡ于术前和术后测定３７例创伤病人和３０例健康志愿者血清Ｅ-ＳＬＴ等浓度。结果：术后合并感染组中：Ｅ-ＳＬＴ和ＩＬ-１０浓度分别于术后第二、３天开始升高，相关系数ｒ＝０.９６４，Ｐ＜０.０５；ｓＣＤ１４与ＴＮＴ-α浓度于术后第１天开始升高，相关系数ｒ＝０８９６，Ｐ＜０．０５。结论：ｓＣＤ１４和ＴＮＦ－ａ、Ｅ－ＳＬＴ和ＩＬ—１０分别与早期感染或严重感染密切相关，是反映术后并发感染病人病情变化和预后的可靠指标之一。

Abstract

Objective To investigate the change in serum levels of E - selectin

interleukin - 10

tumor necrosis factor α

soluble CD14

as well as their relationship to infection during the pathophysiologic process in postoperative patients complicating severe infection. Methods Serum E - selectin

interleukin - 10

soluble CD14 and tumor necrosis factor a levels in 37 postoperative patients were observed by ELISA on the day before operation

and 1st

2nd

3rd

4th

14th and 25th days respectively after operation. Results :There were changes of high levels of E -selectin

interleukin - 10

soluble CD14 and tumor necrosis factor a in postoperative patients complicating systemic infection. The correlation coefficients in the serum levels of E - selectin and interleukin - 10

soluble CD14 and tumor necrosis factor- α were r = 0.963

P<0. 05

r 0.896

P<0. 05

respectively. Conclusion It is suggested that soluble CD14 and tumor necrosis factor a may play an important role during early process of infection

which may be closely related with the occurrence of infection. E - selectin and interleukin - 10

late cellular factors

play important roles in the mechanism of pathogenesis and might be closely related to severe degree of secendary infection during late pathophysiologic process of infection. Increased serum concentration of soluble CD14

tumor necrosis factor a

E - selectin and interleukin - 10 were good prognostic markers on postoperative patients complicating severe infection.

关键词

感染E-选择素白细胞介素-10可溶性CD14

Keywords

infectionE- selectinInterleukin -10Soluble GD14

references

浏览量

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

呼吸过滤器在无创机械通气患者中的应用研究

机械和感染双重法建立中华田园犬宫腔粘连模型

腹部手术前后监测血中PFN、CRP和AT-Ⅲ早期诊断感染的价值

氨基胍对糖尿病大鼠任意尿Pr/Cr比值和感染率的影响

儿科疾病患儿血清中巯基水平的变化及临床意义探讨

术后并发严重盛染患者血清E-选择素、IL-10和sCD14的变化及其与预后的关系

Dynamics of levels of E - selectin, interleukin - 10 and soluble CD14 in serum of pateints complicating severe infection

DOI：10.13406/j.cnki.cyxb.2001.04.026

摘要

Abstract

关键词

Keywords

references

术后并发严重盛染患者血清E-选择素、IL-10和sCD₁₄的变化及其与预后的关系