LIU Bao-qin, et al. The relationship between GH-IGF-I system and IUGR[J]. Journal of Chongqing Medical University, 2001,(4):375-377. DOI: 10.13406/j.cnki.cyxb.2001.04.005.
Objective: To detect the effects of GH-IGF-I system on the idiopathic IUGR.Methods:18 pregnant women with idiopathic IUGR and 25 normal pregnant women were studied to measure the IGF-I and GH levels of maternal serum
umbilical serum
amniotic fluid and placental tissue. Results: The GH
IGF-I levels of maternal serum
umbilical serum and placental tissue in IUGR group were significantly lower than those in control group. The levels of IGF-I were positively correlated with the levels of GH in every sample.Conclusion:During the development of fetus IGF-I and GH system plays an important regulating role.