Detection of chlamydia trachomatis from amniotic fluid and cervical samples at caesarean birth[J]. Journal of Chongqing Medical University, 2000,(2):142-143.
Detection of chlamydia trachomatis from amniotic fluid and cervical samples at caesarean birth[J]. Journal of Chongqing Medical University, 2000,(2):142-143. DOI: 10.13406/j.cnki.cyxb.2000.02.012.
Objective: To study the modes and routes of the vertical Chlamydia trachomatis(Ct) transmission. Methods:Chlamydia trachomatis in the matched maternal-fetal samples(cervices
amniotic fluid and neonatal conjunctivas) was detected by cell culture and polymerase chain reaction(PCR). Results:Of the 102 matched maternal-fetal samples at caesarean birth
24 matched samples of cervices
amniotic fluid and neonatal conjunctivas were positive for Ct by cell culture and PCR; 6 were negative for cervices but positive for amniotic fluid and neonatal conjunctivas; 4 were positive for cervices but negative for amniotic fluid and neonatal conjunctivas; 68 were negative for cervices
amniotic fluid
and neonatal conjunctivas. The Ct transmission rates of pregnant women and newborns were 27.5%(28/102) and 29.5%(30/102)
respectively. Conclusion:Cervical Chlamydia infection was highly related to the amniotic infection.The Ct infection in pregnant women may cause fetal infection and the pathways of intrauterine infection seem to be ascension from cervical access to the amniotic cavity.