Plasma levels of nitric oxide and endothelin-1 and their correlations with blood pressure in patients with essential hypertension[J]. Journal of Chongqing Medical University, 1999,(4):354-357.
Plasma levels of nitric oxide and endothelin-1 and their correlations with blood pressure in patients with essential hypertension[J]. Journal of Chongqing Medical University, 1999,(4):354-357. DOI: 10.13406/j.cnki.cyxb.1999.04.006.
Plasma levels of endothelin - 1(ET- 1) and nitric oxide(NO)were studied in 53 essential hypertensive patientsand 22 healthy controls. Besides
the relationships between plasma levels of ET-1
NO and blood pressurevalues were also analysed. Compared with healthy controls
plasma levels of ET-1 were markedly increasedwhile NO plasma levels obviously decreased(P<0.01).Casual blood pressure values significantly correlated withplasma levels of NO
but not with plasma levels of ET-1. Both ET-1 and NO had fine correlations withambulatory blood pressure paramaters.NO and ET-1 play important roles in initiation and progression ofessential hypertension.