Expressions of proliferating cell nuclearantigen, estrogen receptor and epidermal growth factor receptor in tumors of the gallbladder[J]. Journal of Chongqing Medical University, 1999,(3):230-232.
Expressions of proliferating cell nuclearantigen, estrogen receptor and epidermal growth factor receptor in tumors of the gallbladder[J]. Journal of Chongqing Medical University, 1999,(3):230-232. DOI: 10.13406/j.cnki.cyxb.1999.03.003.
estrogen receptor (ER) and epidermal growth factor receptor(EGFR) in tumor cells in the gallbladder were assayed by the LSAB immunohistochemical method in 33patients.20 of 25 patients with carcinoma were PCNA positive (80%)
which was not related significantly tohistologicaltypes (P>0.05). 15 patients with carcinoma were ER positive (60.0%)
which was related to the PCNA(P<0.01). 7 patients were EGFR positive (28.0%) and most of these were ER negqtive. 5 of 8 patients withadenomawere PCNA positive with expression of ER or EGFR in 4 cases. The study suggests that the ER andEGFR are able to stimulate the proliferation of the tumor cells of gallbladder.There is some regulation betweenER and EGFR .The expressions of PCNA ER and EGFR in some adenomas should be noticed.
关键词
胆囊肿瘤增殖雌激素受体表皮生长因子受体
Keywords
Tumor of the gallbladderHyperplasiaestrogen receptorepidermal growth factor receptor