尼莫通治疗糖尿病周围神经病变的临床初步观察

郭常辉; 严钟德; 钟玲

doi:10.13406/j.cnki.cyxb.1998.04.013

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尼莫通治疗糖尿病周围神经病变的临床初步观察

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- 尼莫通治疗糖尿病周围神经病变的临床初步观察
- Preliminary clinical observation on treating diabetic peripheral neuropathy with Nimotop
- 重庆医科大学学报 1998年第4期页码：356-358
- 作者机构：
  
  1. 重庆医科大学第二临床学院内分泌科
  2. 重庆医科大学第二临床学院内分泌科副教授
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1998.04.013
  中图分类号： R587.2
- 纸质出版日期：1998，
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[1]郭常辉,严钟德,钟玲.尼莫通治疗糖尿病周围神经病变的临床初步观察[J].重庆医科大学学报,1998(04):356-358.

Preliminary clinical observation on treating diabetic peripheral neuropathy with Nimotop[J]. Journal of Chongqing Medical University, 1998,(4):356-358.
[1]郭常辉,严钟德,钟玲.尼莫通治疗糖尿病周围神经病变的临床初步观察[J].重庆医科大学学报,1998(04):356-358. DOI： 10.13406/j.cnki.cyxb.1998.04.013.

Preliminary clinical observation on treating diabetic peripheral neuropathy with Nimotop[J]. Journal of Chongqing Medical University, 1998,(4):356-358. DOI： 10.13406/j.cnki.cyxb.1998.04.013.

摘要

旨在探讨尼莫通对糖尿病周围神经病变（DPN）的临床疗效及可能机制

对56例 DPN 患者予以静滴尼莫通治疗

并分别观察治疗前后临床症状、感觉、运动神经传导速度变化。结果表明:治疗l～2个疗程后

临床有效率达88.9%

神经传导速度（NCV）明显提高

平均每条 NCV 提高2.44m/s

与治疗前相比有非常显著性差异（P<0.01～0.001）

且红细胞聚集指数降低（P<0.05）。提示该药疗效显著

副作用小

是治疗 DPN 的一种较理想的药物。

Abstract

In order to inquire into the clinical curative effect and the mechanism of Nimotop on treating diabetic peripheral neuropathy

56 cases of diabetic peripheral neuropathy(DNP)were treated with Nimotop by means of intravenous drip.The clinical manifestations before and after treatment

conduction velocity of sensory nerve and motor nerve and change of hemorheology were observed then.The result showed that after 1 to 2 courses of treatment

the clinical effective rate was 88.9%

with a notable improvement in nerve conduction velocity.The average rate on each nerve had been increased 2.44m/s.To compare with the situation before treatment

a significiant difference was shown(P<0.01～0.001)

and a decrease in aggregation of red blood corpuscle eas found (P<0.05).All mentioned above have indicated that Nimotop is useful for treating diabetic peripheral neuropathy. It has less side-effect and a fairly good curative effect.

关键词

尼莫通糖尿病周围神经病变

Keywords

NimotopdiabetesPeripheral neuropathy

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