Serum antisperm antibodus in 229 couples wiiii un.xplain .d infirtilii’y (Group A) and 151 infertile couples with determined causes (Group B) were

assayed by a micro-agglutinatioa and iamobilization test.Infertility causes in Group B included sndometriosis

ovarian disfunction

oviduct or csrvix disorders

oligozoosperrnia and asthenozoospermia. Thirty |criile control couples were also studied.Samples from 56 patients in Group A (12.2%; and 30 in Group B(9.9%)were positive for ASA

significantly different from fertile controls (P<0.01 and<0.05

respectively) . In detail

sera from 9.2% of males and 15.3% of females in Group A and 4.6% of males and 15.2% of females in Group B were positive. In both groups

ASA occurrence in female is more frequen i: than in male(P<^0.05). Results suggest that the immunological factor coexists with other infertility factors in some socalled "determined causes" infertile patients

especially in wom-ii