A MORPHOLOGIC STUDY OF PULMONARY HYPOPLASIA IN FETAL RABBITS WITH EXPERIMENTAL DIAPHRAGMATIC HERNIA[J]. Journal of Chongqing Medical University, 1993,(3):188-190.
A MORPHOLOGIC STUDY OF PULMONARY HYPOPLASIA IN FETAL RABBITS WITH EXPERIMENTAL DIAPHRAGMATIC HERNIA[J]. Journal of Chongqing Medical University, 1993,(3):188-190. DOI: 10.13406/j.cnki.cyxb.1993.03.006.
Experimental diahragmatio hernia was created on fetal rabbits during gestaional day (GD) 23-25d
and 8 rases of the model survived in intrauterin’j life up to the full term -were obtained by hysterotomy for morphologic study on pulmonary hypoplsia. At the samatime 20 normal f^tal rabbits on 19-23d were studied for pulmonary development in scries. Four stages of normal fetal lung development
such as pseudoglandular period (19-23d)
canalicular period (23-25d)
sacular period (25-28d)
and alveolar period (28-23d) were demonstrated. While in the experimental models
the pulmonary development were hindered in various. degrees related to the onset of diaphragmatic hernia on GD
and the extent of compression by herniated intra-abdominal organ