Serum contents of sialic acid(SA)

fucose(Fuc)

α1-acid glycoprotein(α1-AG)

α1-antitrypsin (α1-AT)

haptoglobin (HP)

prealbumin (PA) and transferrin (TF) were concomitantly measured in 64 patients with primary hepatocellular carcinoma

63 with nasopharyngeal carcinoma (NPC)

34 with larygocarcinoma (LC)

20 with gastric carcinoma

16 with colorectal carcinoma

60 with benign diseases (BD) and 58 normal blood donors (NBD). The results revealed that serum SA

Fuc

α1-AG

α1-AT and HP contents were all significantly elevated in patients with tne five kinds of cancers mentioned above as compared with NBD.The serum index levels in the five groups Were all significantly higher except in patients with LC than in those with BD. Therefore

measurements of these five indeces are suggested in the non-organic specific serum tumor markers. Furthermore

those five index levels were all significantly higher in patients with Ⅲ

IV phase NPC and LC than in NBD and Ⅰ

Ⅱ NPC and LC. The later the stage was

the more the contents of the five indeces are. The experiment results indicate that the five indeces will help clinical diagnosis

prognosis

therapeutic evaluation