4种抗菌药物对淋球菌体外抗菌活性的研究

秦亚恬; 朱道银

doi:10.13406/j.cnki.cyxb.1991.02.007

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4种抗菌药物对淋球菌体外抗菌活性的研究

更新时间：2024-01-17

- 4种抗菌药物对淋球菌体外抗菌活性的研究
- IN VITRO ANTIBACTERIAL ACTIVITIES OF FOUR ANTIBACTERIAL AGENTS TO NEISSERIA GONORRHEAE
- 重庆医科大学学报 1991年第2期页码：114-117
- 作者机构：
  
  重庆医科大学微生物学教研室
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1991.02.007
  中图分类号：
- 纸质出版日期：1991，
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[1]秦亚恬,朱道银.4种抗菌药物对淋球菌体外抗菌活性的研究[J].重庆医科大学学报,1991(02):114-117.

Qin Yatian Department of Microbiology. IN VITRO ANTIBACTERIAL ACTIVITIES OF FOUR ANTIBACTERIAL AGENTS TO NEISSERIA GONORRHEAE[J]. Journal of Chongqing Medical University, 1991,(2):114-117.
[1]秦亚恬,朱道银.4种抗菌药物对淋球菌体外抗菌活性的研究[J].重庆医科大学学报,1991(02):114-117. DOI： 10.13406/j.cnki.cyxb.1991.02.007.

Qin Yatian Department of Microbiology. IN VITRO ANTIBACTERIAL ACTIVITIES OF FOUR ANTIBACTERIAL AGENTS TO NEISSERIA GONORRHEAE[J]. Journal of Chongqing Medical University, 1991,(2):114-117. DOI： 10.13406/j.cnki.cyxb.1991.02.007.

摘要

本文采用琼脂倍比稀释法检测38株淋球菌对4种抗菌药物的敏感性

并作β-内酰胺酶测定.结果表明

21.1%的菌株对青霉素耐药;7.9%的菌株为PPNG;7.9%的菌株对壮观霉素耐药;而100%的菌株对氟嗪酸、氟哌酸敏感

且MIC

、MIC

值均低.结果显示

应注意淋球菌对青霉素、壮观霉素的耐药性

推荐用氟嗪酸、氟哌酸治疗淋病

Abstract

In vitro susceptibilities of 38 strains of gonococcus to 4 antibacterial agents wers tested by the agar double dilution method.Beta-lactamase of the bacteria was also tested.The rusults showed that in 38 strains of gonococcus 21.1% were penicillin resistant

7.9% were PPNG strains

7.9%were spectinomycin resistant

all of them were susceptible to both ofloxalin and norfloxacin.The MIC50 and MIC90 of ofloxacin and norfloxacin were very low.It was indicated thaat much attention should be paid to the resistance of gorcccccus to penicillin and spectinomycin. Ofloxacin and norfloxacin should be recommended in treatment of gonorrhea

关键词

淋球菌最低抑菌浓度青霉素壮观霉素氟嗪酸氟哌酸

Keywords

Neisselia generrheaeMinimum inhibitory concentration(MIC)PenicillinSpectinomycinOfloxacinNorfloxacin

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