Combined chemotherapy and radiation therapy were given to 114 patients with NPC during January 1982-December 1983. Nine

49 and 56 were in stage II

III and IV (The Fifth National Con-gress of NPC

Changsha

1979) respectively. CTX (Cytophospha-mide). 5FU (5-Fluorouracil) and VCR (Vincristine). or CTX and 5FU

CTX and VCR were administrated introvenously before radiation therapy. The radiation therapy was given in two courses with about 3 weeks interval. The 5-year survival rates were 66.7 %(7/9) in stage II

62.8%(34/49) in stage III and 48.8%(31/56) in stage IV (P>0.05). The results shown that CTX

5FU

and VCR were available and suggested that chemo. therapy may be necessary for patients with NPC before relapse or metastasis was detected