Li Qifu et al. THE ALTERATION OF T-LYMPHCYTE NUMBER AND PERITONEAL MACROPHAGE PHAGOCYTOSIS IN STREPTOZOTOCIN-INDUCED DIABETIC MICE[J]. Journal of Chongqing Medical University, 1990,(4):262-265.
Li Qifu et al. THE ALTERATION OF T-LYMPHCYTE NUMBER AND PERITONEAL MACROPHAGE PHAGOCYTOSIS IN STREPTOZOTOCIN-INDUCED DIABETIC MICE[J]. Journal of Chongqing Medical University, 1990,(4):262-265. DOI: 10.13406/j.cnki.cyxb.1990.04.002.
The peripheral T-lymphocyte number and phagocytic function of peritoneal macro-phages were studied in diabetic C57 mice induced by streptozotocin.. No significant difference in the peripheral lymphcyte number was found
but the percentage of T-lymphocytes quantitated by ANAE staining significantly decreased in diabetic mice. The phagocytic activity of yeasts by peritoneal macrophages was apparently lower in diabetic mice than in normal control. The decrease of T-lymphocytes and depressed phagocytosis of macrophages suggest impaired function of cell-mediated immunity in streptozotocin-induced diabetic mice