The contractile function of gall-bladder and the cardioautonomic nervous dysfunction were tested in 49 normal controls and 83 diabetics

among these patients 51 had autonomic neuropathy and the others did not. The results showed that the contractile dysfunction of gall-bladder was increased in 37 of 83(44

6%) and normol in the controls. It was higher in the diabetic patients with symptpms of autonomic neuropathy than in those without

and the difference was significant (p<0.01). The incidence and severity of the contractile dysfunction of gallbladder and caridac autonomic nerve dysfunction in these patients were quite consistent. Our results suggested that the diabetic autonomic neuropathy is a general lesion

and functional test of autonomic nerve seems to be quite helpful to the early diagnosis of diabetic autonomic neuropathy