THE THERAPEUTIC EFFECT WITH SHORT-TERM ANTITHYROID DRUG THERAPY IN HYPERTHYROIDISM[J]. Journal of Chongqing Medical University, 1988,(1):43-46. DOI: 10.13406/j.cnki.cyxb.1988.01.013.
短程药物治疗甲状腺功能亢进症的疗效观察
摘要
本文观察20例初发未治疗的Graves病患者
采用他巴唑单剂短程疗法.于治疗前、缓解停药时及停药半年后测定甲状腺功能、血清Ig及血清酶等
以观察其缓解率及探讨与复发的有关因素.随访观察27月
其结果缓解与复发各占10例
缓解率为50%
与经典的长程分次药物疗法相仿.治疗终止时
甲状腺仍有血管杂音者易复发
Abstract
Twenty previously untreated patients with Graves’ disease were treated with short-term methimazole therapy. The thyroid function
serum Ig and serum enzyme were determined before and at the end of the treatment and also six months after treatment. The results showed that ten of the twenty patients remained remission(50%)
the remission rate of short-term antithyroid drug therapy with single daily dose was similar to that of classical one
The disease was easily to relapse if the blood vessel murmur of the thyroid gland was still heard at the end of treatment