We reviewed fourty cases of pancreato-duodenectomy in the past twenty five years. There were seventeen cases had early complications. The complication rate was 42.5%. There were 5 cases died

the operative mortality rate was 12.5%

The following factors had relation tooperative death and to operative complication :(1) inadequate preoperative preperation. (2) incorrectdecision of resectability’

especialy the tumor located near crochet. (3) massive bleedingin operation. (4) prevent secondary postoperative hemorrhage. (5) meticulous care in performing pancreatic jejuaal anastomoses for prevention of pancreatic fistula. (6) reduction of intraoperative contamination for prevention of postoperative abdominal abscess