血清铁蛋白和铁蛋白/转铁蛋白比值诊断肝癌及慢性肝病的临床意义

吴小翎; 沈鼎明

doi:10.13406/j.cnki.cyxb.1986.03.006

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血清铁蛋白和铁蛋白/转铁蛋白比值诊断肝癌及慢性肝病的临床意义

更新时间：2024-01-17

- 血清铁蛋白和铁蛋白/转铁蛋白比值诊断肝癌及慢性肝病的临床意义
- THE CLINICAL VALUE OF SERUM FERRITIN AND THE RATIO OF SERUM FERRITIN/TRANSFERRIN IN HEPATOCELLULAR CARCINOMA ANDCHRONIC LIVER DISEASES
- 重庆医科大学学报 1986年第3期页码：164-168
- 作者机构：
  
  重庆医科大学第二医院内科消化组
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1986.03.006
  中图分类号：
- 纸质出版日期：1986，
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[1]吴小翎,沈鼎明.血清铁蛋白和铁蛋白/转铁蛋白比值诊断肝癌及慢性肝病的临床意义[J].重庆医科大学学报,1986(03):164-168.

Second Hospital Wu Xiaoling. THE CLINICAL VALUE OF SERUM FERRITIN AND THE RATIO OF SERUM FERRITIN/TRANSFERRIN IN HEPATOCELLULAR CARCINOMA ANDCHRONIC LIVER DISEASES[J]. Journal of Chongqing Medical University, 1986,(3):164-168.
[1]吴小翎,沈鼎明.血清铁蛋白和铁蛋白/转铁蛋白比值诊断肝癌及慢性肝病的临床意义[J].重庆医科大学学报,1986(03):164-168. DOI： 10.13406/j.cnki.cyxb.1986.03.006.

Second Hospital Wu Xiaoling. THE CLINICAL VALUE OF SERUM FERRITIN AND THE RATIO OF SERUM FERRITIN/TRANSFERRIN IN HEPATOCELLULAR CARCINOMA ANDCHRONIC LIVER DISEASES[J]. Journal of Chongqing Medical University, 1986,(3):164-168. DOI： 10.13406/j.cnki.cyxb.1986.03.006.

摘要

本文检测38例肝细胞性肝癌和42例其他肝病患者的血清铁蛋白（SF）和转铁蛋白（TFN）

并计算SF/TFN比值。结果证实肝癌组SF增高

SF/TFN亦显著增高

且后者与失代偿性肝硬化组的重叠较少。对肝病患者

如SF/TFN≥4

应考虑恶变可能

Abstract

Serum ferritin (SF) and transferrin (TFN) level were measured in 38 patients with hepatoce-llular carcinoma (HCC) and in 42 comparable subjects with chronic live diseases

while the ratio of SF/TFN in each group was calculated respectively .Although either SF concentration

or the ratio of SF/TFN in the group of HCC was elevated

the latter was less than the former in the over- lap of the range of concentration between HCC and cirrhosis. We have confirmed that SF as a marker of HCC is useful

but the diagnostic speciality of SF is worse. More valuable parameter in the diagnosis of HCC

specially in that of AFP-negative HCC

is the ratio of SF/TFN. Decreased TFN concentration may reflect the degree of damaged liver

but it has no role in diagnosis of HCC. If SF/TFN ratio of a patient with liver disease is>4

diagnosis of the patient would be highly suspected to be HCC

关键词

铁蛋白转铁蛋白肝细胞癌肝硬化

Keywords

Ferritintransferrinhepatocellular carcinomaliver cirrhosis

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