THE ANALYSIS OF SCE,Ag-NOR ANDAg-AA FOR THE BALANCED TRANSLOCATION CARRIERS[J]. Journal of Chongqing Medical University, 1986,(2):78-82. DOI: 10.13406/j.cnki.cyxb.1986.02.003.
染色体平衡易位携带者的SCE、Ag—NOR和Ag—AA分析
摘要
本文将3例染色体平衡易位携带者的SCE、Ag—NOR和Ag—AA与正常对照进行对比分析
提示平衡易位携带者的染色体稳定性较差
罗伯逊易位携带者丢失的rRNA基因可由其他近端着丝粒染色体上的rRNA基因活性来补偿
近端着丝粒染色体联合频率的增高可能与染色体不分离和易位的形成有关。
Abstract
The SCE
Ag-NOR and Ag-AA of the three cases of balanced translocation carriers had been investigated
and compared with that of 12 normal individuals.The results indicated that the stability of chromosomes in the balanced translocation carriers was less than that in the normals. The loss of rRNA genes of the Robertsonian translocation carriers can be compensated by the activity of rRNA genes on the other chromosomes.The frequency of acrocentric chromosomal association may be related to nondisjunction.