缺陷型精神分裂症认知功能与病耻感相关性研究

梁丹丹; 许晨晨; 何孔亮; 靳胜春

doi:10.13406/j.cnki.cyxb.002930

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缺陷型精神分裂症认知功能与病耻感相关性研究

认知障碍心理评估 | 更新时间：2022-06-24

- 缺陷型精神分裂症认知功能与病耻感相关性研究
- On the relevance between cognitive function and stigma in patients with deficit schizophrenia
- 重庆医科大学学报 2021年46卷第11期页码：1328-1333
- 作者机构：
  
  安徽医科大学附属心理医院，合肥　230022
- 作者简介：
  
  梁丹丹，Email：1563465537@qq.com，研究方向：精神分裂症认知功能的研究及干预。
  靳胜春，Email：2023591831@qq.com。
- 基金信息：
  
  合肥市卫健委2019年应用医学研究重点项目第15项;安徽医科大学校科研基金资助项目(2019xkj199)
- DOI：10.13406/j.cnki.cyxb.002930
  中图分类号： R749.3
- 纸质出版日期：2021-11-28，
  
  收稿日期：2021-06-29，
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梁丹丹, 许晨晨, 何孔亮, 等. 缺陷型精神分裂症认知功能与病耻感相关性研究[J]. 重庆医科大学学报, 2021,46(11):1328-1333.

Dandan Liang, Chenchen Xu, Kongliang He, et al. On the relevance between cognitive function and stigma in patients with deficit schizophrenia[J]. Journal of Shanxi Agricultural Sciences, 2021,46(11):1328-1333.
梁丹丹, 许晨晨, 何孔亮, 等. 缺陷型精神分裂症认知功能与病耻感相关性研究[J]. 重庆医科大学学报, 2021,46(11):1328-1333. DOI： 10.13406/j.cnki.cyxb.002930.

Dandan Liang, Chenchen Xu, Kongliang He, et al. On the relevance between cognitive function and stigma in patients with deficit schizophrenia[J]. Journal of Shanxi Agricultural Sciences, 2021,46(11):1328-1333. DOI： 10.13406/j.cnki.cyxb.002930.

摘要

目的：

探讨缺陷型精神分裂症患者认知功能损害及其阴性症状与病耻感之间的关联性。

方法：

收集72例稳定期精神分裂症患者，采用RBANS量表、Stroop测试、Link系列病耻感量表测量其认知功能及病耻感，后根据缺陷型精神分裂症诊断量表（SDS量表）分为缺陷型组（29例）与非缺陷型组（43例），并招募正常对照组40例，采用RBANS、Stroop测试测量其认知功能。

结果：

缺陷型精神分裂症患者在RBANS量表（

0.05）及病耻感量表除教育（

0.05）外各维度评分（

0.05）明显高于非缺陷型精神分裂症；Stroop测试中缺陷型精神分裂症在各组测试用时明显高于非缺陷型组（

0.05）；72例精神分裂症患者斯皮尔曼相关分析提示RBANS各维度与贬低-歧视、退缩、应对、误解、不同/羞耻、情感体验、病耻感总分斯皮尔曼相关系数绝对值

0.3，呈负相关关系；Stroop测验各维度评分以色时间与贬低-歧视、不同/羞耻、情感体验、病耻感总分斯皮尔曼相关系数绝对值

0.3，字时间与除保密、教育、挑战、分离、应对外各维度斯皮尔曼相关系数绝对值

0.3，色字时间与除保密、教育、挑战、分离外各维度斯皮尔曼相关系数绝对值

0.3，以色字时间-字时间与病耻感除教育、分离维度外各维度斯皮尔曼相关系数绝对值

0.3，呈正相关关系；SDS量表评分与病耻感相关性分析提示除教育外各维度斯皮尔曼相关系数均

0.3，呈正相关关系。

结论：

缺陷型精神分裂症较非缺陷型精神分裂症认知功能损害及病耻感更严重；相关分析结果提示病耻感与非社会认知功能损害存在负相关关系，与阴性症状存在适度的正相关。

Abstract

Objective

To explore the relationship between cognitive impairment

negative symptoms and stigma in patients with deficit schizophrenia.

Methods

There were 72 patients with stable schizophrenia who were collected in the study. Their cognitive function and stigma were measured with RBANS scale

Stroop test and Link series of stigma scales. Then they were divided into deficit group (29 cases) and non-deficit group (43 cases) according to the schedule for the deficit syndrome (SDS). Besides

40 normal controls were recruited in the surrounding community

and their cognitive function was measured by RBANS scale and Stroop test.

Results

The scores of all dimensions except education (

0.05) in RBANS scale (

0.05) and stigma scales (

0.05) of patients with deficit schizophrenia were significantly higher than those of non-deficit schizophrenia patients. In Stroop test

the test time of deficit patients was significantly longer than that of non-deficit patients (

0.05). Spearman correlation analysis of 72 schizophrenic patients showed that the absolute value of Spearman correlation coefficient between each dimension of RBANS and devaluation discrimination

withdrawal

coping

misunderstanding

difference/shame

emotional experience and total score of stigma was greater than 0.3

showing a negative correlation. The absolute value of Spearman correlation coefficient between color time and derogation discrimination/shame

emotional experience and total score of stigma in each dimension of Stroop test was greater than 0.3.That between word time and all dimensions except confidentiality

education

challenge

separation and response was greater than 0.3; that between color word time and all dimensions except confidentiality

education

challenge and separation was greater than 0.3

and between color word time word time and stigma was greater than 0.3 except for education and separation. These absolute values greater than 0.3 showed a positive correlation. The correlation analysis between SDS score and stigma showed that the Spearman correlation coefficients of all dimensions except education were greater than 0.3

showing a positive correlation.

Conclusion

The cognitive impairment and stigma are more serious in the patients with deficit schizophrenia than in those with non-deficit schizophrenia. The results of correlation analysis suggest that there is a negative correlation between stigma and non-social cognitive impairment

and a moderate positive correlation with negative symptoms.

关键词

缺陷型精神分裂症认知功能阴性症状病耻感关联性

Keywords

deficit schizophreniacognitive functionnegative symptomsstigmarelevance

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